1. GSH responsive AuNRs@TFF nanotheranostic for NIR-II photoacoustic imaging-guided CDT/PTT synergistic cancer therapy,2024年9月发表于Biomaterials Advances
该研究使用过渡金属(铁)和天然多酚单宁酸形成的金属多酚网络结构,用来修饰金纳米棒的表面(AuNRs@TF),并使用靶向功能分子巯基叶酸对AuNR的表面进行了改性(AuNRs@TFF),具有良好的生物相容性和肿瘤靶向能力,扩展了AuNRs在纳米医学领域的应用。研究使用巨哥科技的红外热像仪测量AuNRs@TFF溶液(50μg/mL)和水,用1064nm的激光照射10分钟(1W/cm2)的温度变化:Photothermal heating experiments were performed using an infrared thermal imager (MAG30, Magnity Electronics, China).
2. VEGFB promotes adipose tissue thermogenesis by inhibiting norepinephrine clearance in macrophages,2024年10月发表于BBA-Molecular Basis of Disease
该研究确定了血管内皮生长因子B(VEGFB)/血管内皮生长因子受体1(VEGFR1)信号在改善白色脂肪组织(WAT)产热中的重要作用。研究使用巨哥科技的红外热像仪测量VEGFB/VEGFR1对小鼠在常温和低温环境下体温的影响:A T335 infrared digital thermal imaging camera (MAG34, Magnity Technologies, China) was used to record surface temperatures.
3. Injectable dual-network hyaluronic acid nanocomposite hydrogel for prevention of postoperative breast cancer recurrence and wound healing,2024年12月发表于International Journal of Biological Macromolecules
该研究开发了一种由鲱鱼精DNA(hsDNA)桥接甲基丙烯酸HA(HAMA)和FeMg-LDH-ppsa纳米杂化螯合邻苯二酚改性HA(HADA)组成的双网透明质酸(HA)纳米复合水凝胶,用于预防癌症复发、抗感染和促进伤口愈合。研究使用巨哥科技的红外热像仪观测四种不同的水凝胶在808nm激光照射(10分钟,0.5Wcm-2)下的热图图像以及相应的温度变化:During irradiation, the real-time temperature and photothermal images were recorded using an IR thermal imaging camera (Magnity Electronics, MAG30).
4. A One-Stone-Two–Birds Strategy for Intervertebral Disc Repair: Constructing a Reductive Chelation Hydrogel to Mitigate Oxidative Stress and Promote Disc Matrix Reconstruction,2024年12月发表于Advanced Materials
该研究通过透明质酸接枝硫脲(HA-NCSN)与Cu2+的还原螯合,设计了一种动态水凝胶(HA-NCSN/Cu),具有可注射性、自修复性、活性氧(ROS)清除能力和光热性能等特点,在治疗椎间盘退变(IVDD)方面具有巨大潜力。研究使用巨哥科技的红外热像仪观测近红外(NIR)激光照射后10分钟内,不同Cu2+浓度的水凝胶的温度变化情况:The temperature evolutions atdifferent time intervals were recorded and analyzed with Magnity Electronics tools systems, recording the temperature every 10s within 10min.
5. Flexible dual-mode epidermal sensor for time-sharing muscle fatigue monitoring and photothermal therapy,2025年1月发表于Chemical Engineering Journal
该研究开发了一种用于力检测和光热治疗的灵活双模表皮传感器,具有超宽检测范围、高灵敏度、出色的压力检测循环稳定性,以及用于光热治疗的快速光热转换,可以检测人体运动,并基于分时复用技术进行光疗,具有医疗保健潜力,特别是监测和及时缓解肌肉疲劳。研究使用巨哥科技的红外热像仪记录不同样品暴露于808nm激光下的温度变化情况:Photothermal images were captured using an infrared (IR) camera (MAG30, Magnity Electronics, China). Temperature signals were analyzed using Magnity Electronics tool systems.
6. Saikosaponin D ameliorates obesity and metabolic disorders via the gut microbiota-SCFAs-thermogenic fat axis,2025年2月发表于Food Bioscience
该研究通过从传统草药产品柴胡中提取的柴胡皂苷D(Sa-D)激活棕色脂肪组织(BAT)中的产热程序,通过消耗能量来对抗肥胖。研究使用巨哥科技的红外热像仪测量在冷刺激后,经Sa-D处理的小鼠皮肤温度和与高脂饮食(HFD)喂养的小鼠皮肤温度对比:Mice were placed on ice for 2h of cold stimulation, then anaesthetized by intraperitoneal injection of sodium pentobarbital, and immediately imaged with an infrared thermography camera (Magnity Electronics, Shanghai, China).
7. Transdermal microneedle-assisted ultrasound-enhanced CRISPRa system to enable sono-gene therapy for obesity,2025年2月发表于Nature Communications
该研究开发了一种可控的微针(MN)药物递送平台,一是通过声动力疗法杀死多余的白色脂肪细胞,二是通过CRISPRa-UCP1系统的可控释放和声动力效应促进白色脂肪细胞的褐变,用于声控基因治疗来对抗肥胖。研究使用巨哥科技的红外热像仪观测不同处理的小鼠体温随时间变化:The skin temperature in the BAT region were recorded with an infrared thermal imaging camera (Magnity Electronics).
8. A vascular heterogeneity-orienting TACE strategy addresses peripheral tumor and avascular deep tumor for complete hepatocellular carcinoma clearance,2025年3月发表于Chemical Engineering Journal
该研究设计了一种非牛顿流体MPMT凝胶,在HCC血管中表现出选择性栓塞,并在栓塞后消除了缺氧和无血管残留的肿瘤组织,同时最大限度地减少了对常氧健康组织的重大损伤,并发现薄荷醇可以通过降低EGFR表达来抑制肿瘤血管生成和肺转移。研究使用巨哥科技的红外热像仪观测近红外激光照射后注射MPMT凝胶的小鼠肝动脉和肝肿瘤的红外热成像图像:An infrared camera (MAG62-25-150, Magnity Electronics Co., Ltd. Shanghai, China) was used to record the dynamic thermal change.
9. A hydrogel crosslinked with mixed-valence copper nanoclusters for diabetic wound healing,2025年5月发表于Acta Biomaterialia
该研究通过Cu2+离子与硫脲接枝透明质酸(HA-NCSN)的还原金属-配体配位组装,开发了一种可注射的混合价态铜纳米簇交联水凝胶(HS-Cu),通过结合光热疗法(PTT)和电刺激(ES)有效对抗细菌并加速组织再生,有效解决了糖尿病伤口愈合中的关键挑战,包括抑制细菌感染、减轻氧化应激和加速组织再生,从而显著促进伤口愈合。研究使用巨哥科技的红外热像仪来评估HS-Cu水凝胶的光热稳定性:The temperature changes at different time intervals were recorded and analyzed using the Magnity Electronics tool system, with
temperature measurements taken every 10s for a duration of 10min. Subsequently, the photothermal stability of the HS-Cu hydrogel was evaluated by performing 5 photothermal cycles.
10. Construction of biodegradable benzobisthiazole-based onjugated polymers with pendant β-cyclodextrin for synergistic mild-temperature chemo-photothermal therapy,2025年5月发表于Materials & Design
该研究合成了带有侧β-环糊精基团的苯并双噻唑基共轭聚合物(DPD-CAN-OH),将阿霉素(Doxorubicin)负载到DPD-CAN-OH上,得到DPD-CAN-OH-DOX制剂,具有小粒径、高水分散性、优异的光热转换效率和良好的生物可降解性,为多功能光热剂的设计和制备提供了有价值的新见解,以实现有效的癌症治疗。研究使用巨哥科技的红外热像仪测量不同浓度、不同功率激光照射条件下DPD-CAN-OH、DPD-CAN-OH-DOX溶液温度变化情况:Thermal imaging was performed using the Magnity thermal imager.
11. Targeting suppressive feedback of adenosine immunometabolic pathway by tumor cell membranes-coated nanocapsules for chemo-photothermal therapy and enhanced immunotherapy,2025年5月发表于Chemical Engineering Journal
该研究设计了基于肿瘤细胞膜(TM)包覆的仿生介孔聚多巴胺纳米颗粒(MPDAs)与阿霉素(DOX)和ADO抑制剂(PSB)(DOX+PSB@MPDAs@TM)的理想纳米胶囊,可以干扰免疫抑制代谢物腺苷的产生,对抗肿瘤治疗具有潜在的临床价值。研究使用巨哥科技的红外热像仪拍摄经指定处理后,在激光照射(808纳米,0.5瓦/平方厘米,5分钟)期间荷瘤小鼠的热成像图:The corre sponding temperature changes during laser irradiation were monitored using an infrared camera (MAGNITY f15F1)
12. Non-Invasive Multivariate Prediction of Human Thermal Comfort Based on Facial Temperatures and Thermal Adaptive Action Recognition,2025年5月发表于Energies
该研究提出了一种采用非侵入性检测方法的多元融合预测策略,YOLOv5算法结合红外热像仪用于提取面部关键区域的皮肤温度,使用Mediapipe工具和随机森林算法来识别人类的热适应行为。通过将面部温度和基于热自适应动作的预测结果与PMV结果相结合,预测人体的热舒适水平。研究使用巨哥科技的双光红外热像仪同时拍摄人体红外图像及可见光图像,获取体表温度:A binocular infrared thermal imager MAG-RT384 (MAGNITY,China) is placed in front of the subject (2m,90°). The equipment has the temperaturemeasurement accuracy of 0.4℃, visible light resolution of 1920×1080, and infrared resolution of 384×288.
13. In situ therapeutic tumor-associated macrophage vaccines: Biomimetic hybrid metalloenzymes for effective combined tumor immunotherapy,2025年7月发表于Chemical Engineering Journal
该研究开发了一种新型仿生杂化金属酶(BHM)策略,模仿天然金属酶催化作用,重塑代谢性ITME并重振TAM抗原呈递,用于构建治疗性TAM疫苗。研究使用巨哥科技的红外热像仪拍摄使用808纳米激光照射后PB@LOX和纯水的温度变化:Photothermal images and temperature profiles of PB@LOX and pure water were captured at 0-10min intervals using an 808nm laser (1.0W cm-2) and recorded via a thermal imaging amera (Magnity Electronics, MAG30, China).
以上为近一年生命科学领域使用巨哥科技热像仪开展的科学研究工作,巨哥科技致力于为前沿科学研究领域提供科学级精准测温热像仪,助力科研人员取得一流的科研成果。获取更多新品科学级热像仪资讯,请拨打客服热线:4008081320。